2 Days in Rome: The Perfect Itinerary to see the best of the Eternal City
Experience the best of 2 days in Rome! Visit the Colosseum, Vatican, and Trevi Fountain with this perfect itinerary. Maximize your time in the Eternal City!

This post might have affiliate links. Buy purchasing anything through our links you will be helping support us, at no extra cost to you.
Read our statement
Only 2 days in Rome? It may seem impossible to truly experience the Eternal City in such a short time, but with the right itinerary, you can explore its most iconic sights without feeling rushed.
From marveling at the Colosseum and tossing a coin into the Trevi Fountain to exploring the Vatican Museums and savoring a plate of authentic carbonara in Trastevere, this guide will help you maximize your time and enjoy every moment.
Let’s dive in and discover how to experience the best of Rome in just 48 hours!
Is 2 Days in Rome Enough?
Absolutely! While two days in Rome won’t be enough to see everything, it’s plenty of time to explore the city’s most iconic attractions and immerse yourself in its rich history. In just 48 hours, you can visit legendary landmarks like the Colosseum, Vatican Museums, Trevi Fountain and Pantheon, all while savoring authentic Italian cuisine and enjoying leisurely strolls through the city's charming neighborhoods.
This itinerary is designed to help you make the most of your time, covering must-see sights while allowing moments to relax and explore at your own pace. If you want to maximize your visit, consider purchasing a Roma Pass — it provides skip-the-line access to major attractions and unlimited public transport, helping you save both time and money!
Day 1: Ancient Rome & Iconic Landmarks
Rome is a city rich in history and your first day is dedicated to discovering its ancient ruins. Prepare for a journey through time, from the magnificent Colosseum to the enchanting streets of Trastevere.
Morning: The Colosseum & Roman Forum

Start your two-day adventure in Rome with a visit to its most iconic landmark: the Colosseum.
To make the most of your experience, it’s best to purchase Colosseum tickets in advance so you can skip the long lines. Consider opting for a combo ticket, which also grants you access to the Roman Forum and the Palatine Hill.
Arriving early—before 9 AM—will help you beat the crowds and capture stunning photos in the soft morning light.
After exploring the Colosseum, continue your journey through history at the Roman Forum, once the bustling heart of ancient Rome. Then, make your way up to the Palatine Hill, the legendary birthplace of the city, where breathtaking views of the ancient ruins await.
Lunch Near the Pantheon
After a morning immersed in the wonders of ancient Rome, it’s time for a well-deserved break. The Pantheon area offers a wide selection of excellent dining spots, whether you’re looking for a quick, budget-friendly meal or a more traditional Roman experience.
For a simple satisfying lunch, Pasta e Vino is a fantastic choice, serving fresh homemade pasta at affordable prices. If you prefer the charm of a classic trattoria, Armando al Pantheon is a beloved local gem, known for its authentic Roman dishes and a cozy atmosphere.
Afternoon: Trevi Fountain, Pantheon & Piazza Navona

With renewed energy, it’s time to explore some of Rome’s most iconic landmarks. The Trevi Fountain, one of the most famous fountains in the world, is just a short walk away. Don’t forget to throw a coin over your left shoulder – according to the legend you’ll for sure return to the Eternal City.
Early afternoon is the best time to visit this place, when the morning crowds have thinned out and the sun is shining on the marble statues.

Just a few minutes away is the Pantheon. This architectural wonder with its enormous un-reinforced concrete dome has been standing for nearly 2,000 years. Admission is free and when you look up at the oculus, which is open to the sky, you’ll see why this temple has been enchanting visitors for centuries.

To round out your afternoon, head to Piazza Navona, one of the most beautiful squares in Rome. Sit on a bench, take in the fountains, watch the street performers and soak up the Baroque magic of this historic piazza. And finish off with a creamy gelato from one of the nearby gelaterias.
Evening: Trastevere & Traditional Roman Dinner
As the sun sets, make your way to Trastevere, one of Rome’s most authentic and enchanting districts. Its cobblestone streets, ivy-covered buildings and hidden piazzas make it feel like a world of its own. This is the perfect place to slow down and experience Rome like a local.
Start by wandering through its winding alleys, stopping to admire historic churches like Santa Maria in Trastevere, one of the oldest in the city.

As the evening unfolds, settle into a cozy trattoria for a traditional Roman dinner. Da Enzo al 29 is a must-visit for pasta lovers, known for its perfectly executed cacio e pepe and carbonara. If you’re looking for a more intimate setting, Taverna Trilussa serves classic Roman dishes in a warm, rustic atmosphere.
To end the night, take a leisurely stroll along the Tiber River, where the soft glow of streetlights reflects on the water, creating a magical atmosphere. It’s the perfect way to wrap up a day filled with history, culture and unforgettable flavors.
Day 2: Vatican City & Hidden Gems
Your second day in Rome is all about art, history and breathtaking views. You’ll explore Vatican City, admire Michelangelo’s Sistine Chapel, stroll along the Tiber River and wrap up your trip with a stunning sunset at the Spanish Steps.
Morning: Vatican Museums, Sistine Chapel & St. Peter’s Basilica

Start your day early with a visit to Vatican City, one of the most iconic and visited landmarks in the world. The Vatican Museums house an extraordinary collection of art, including the Raphael Rooms and the impressive Gallery of Maps. The real highlight, however, is the Sistine Chapel, where Michelangelo’s legendary frescoes will leave you speechless.
To avoid long lines, it's best to book your Vatican Museums tickets online in advance or opt for a guided tour for a more immersive experience.
After visiting the museums, step inside St. Peter’s Basilica, an architectural masterpiece that dominates St. Peter’s Square. If you're up for it, climbing to the top of the Dome offers one of the best panoramic views of Rome—a moment you won’t forget.

Lunch Near the Vatican
After a morning of art and history, it’s time to refuel. Close to the Vatican, you'll find great spots to enjoy an authentic Roman lunch.
If you’re in the mood for something casual, Pizzarium Bonci serves some of the best pizza al taglio (Roman-style pizza by the slice). For a sit-down experience, Hostaria Dino e Toni offers traditional pasta dishes in a warm, family-run atmosphere.
Afternoon: Castel Sant’Angelo & Villa Borghese

Leaving Vatican City, take a leisurely stroll along the Tiber River toward Castel Sant’Angelo. Originally built as a mausoleum for Emperor Hadrian, this imposing fortress later became a papal refuge and even a prison. Climbing to the top terrace rewards you with stunning views of Rome and the Vatican.
If you have extra time and want to immerse yourself in nature, head to Villa Borghese, the city’s most beautiful park. You can rent a bike, enjoy a relaxed walk or visit the Borghese Gallery, home to masterpieces by Bernini, Caravaggio, and Raphael.

Evening: Sunset at the Spanish Steps & Farewell Dinner
As your time in Rome comes to an end, there’s no better way to say goodbye than watching the sunset from the Spanish Steps. Climbing to the top of the staircase, you’ll be rewarded with a spectacular view of Rome bathed in golden light.

For your final dinner, consider Ristorante Dal Bolognese in Piazza del Popolo, known for its refined Italian cuisine and elegant atmosphere. If you prefer a more laid-back and authentic experience, Trastevere is the perfect place to enjoy one last traditional Roman meal. Nannarella and Tonnarello are excellent choices, offering classic dishes like carbonara and amatriciana in a warm, welcoming setting.

Where to Stay for Visiting Rome in 2 Days?
Staying in the Centro Storico puts you right in the heart of the city, with landmarks like the Pantheon and Trevi Fountain just a short walk away. It’s perfect for first-time visitors who want to immerse themselves in Rome’s history, but prices can be higher.
Monti, a charming neighborhood near the Colosseum, offers a mix of history and trendy cafés, making it a great choice for travelers looking for a lively yet authentic experience.
For those who prefer a more local feel, Trastevere is an excellent option. This district is known for its picturesque streets, traditional trattorias and a vibrant nightlife scene.
If budget is a priority, the Termini area provides affordable accommodations with convenient transport links, though it lacks the charm of other districts.
Meanwhile, Prati, near the Vatican, offers a quieter and more elegant atmosphere, ideal for families or those seeking a more relaxing stay.

How to Move Around Rome?
Rome’s Metro system is the fastest way to cover longer distances, with two main lines, A and B, connecting key attractions like the Vatican, Spanish Steps and Colosseum. However, since many historic landmarks are not directly served by the metro, buses and trams are often necessary.
Buses cover nearly every part of the city, though they can be slow due to traffic. The tram system, though limited, offers a scenic and reliable alternative for reaching areas like Trastevere.
For unlimited travel on public transport, the Roma Pass can be a great option, especially if you plan to visit major attractions. It includes free transport and discounted entry to museums, making it ideal for budget-conscious travelers.
Taxis and rideshare apps like Uber are available but can be expensive and often affected by Rome’s traffic congestion. If you’re in a hurry, using licensed taxi stands rather than hailing a cab on the street is the safest option.
Final Tips for a Perfect Rome Weekend
Spending two days in Rome is an unforgettable experience, but making the most of your time requires a little planning. Book your Colosseum and Vatican tickets in advance to skip long lines and consider getting a Roma Pass for public transport plus attraction discounts. Stay in a central neighborhood like Centro Storico, Monti or Trastevere to minimize travel time.
Most importantly, embrace the Roman way of life—take leisurely strolls, savor every meal and allow yourself moments to simply soak in the beauty of the Eternal City. Whether it’s tossing a coin into the Trevi Fountain, watching the sunset from the Spanish Steps or getting lost in the charm of Trastevere, your 48 hours in Rome will leave you longing to return. Buon viaggio!

We are a Milan-based Travel Blog that aims to be your ultimate guide to the best attractions, food and drink, and things to do to inspire you when planning your holiday!
Do check out our website regularly for awesome travel and expat tips!